Upper airway collapsibility in habitual snorers and sleep apneics: evaluation with drug-induced sleep endoscopy.
نویسندگان
چکیده
Increased upper airway collapsibility has been suspected of being involved in the pathogenesis of sleep-related diseases. It is assumed that patients with severe obstructive sleep apnea syndrome (OSAS) show a stronger collapse of the upper airway compared with habitual snorers. It was the objective of this study to analyze the patterns of upper airway collapse in habitual snorers and patients with OSAS and to correlate these results with data from polysomnography. Endoscopy was carried out during drug-induced sleep (with propofol) and collapsibility was analyzed at two major levels (palatal and tongue base). A total of 207 habitual snorers and 117 patients with OSAS underwent endoscopy after overnight polysomnography in our sleep laboratory. In 95% of cases we were able to induce snoring during drug-induced sleep. The collapsibility in the area of the base of the tongue correlated with higher values of the respiratory disturbance index (RDI) as recorded by standard polysomnography. Patients with OSAS showed significantly stronger collapsibility compared with snorers. The difference was more evident at the tongue-base level. We found no significant correlation between the applied CPAP pressure and collapsibility in patients with OSAS. These results show that collapsibility at the tongue-base level is a factor relevant in sleep-related breathing disorders.
منابع مشابه
Upper airway size and collapsibility in snorers: evaluation with digital fluoroscopy.
This study addressed the question of whether there are any differences in the size and collapsibility of the upper airway measured by digital fluoroscopy, between snorers and controls whilst they were awake and breathing normally; and whether there are any correlations between these measurements and other clinical data. The dynamic changes of the upper airway size were evaluated using digital f...
متن کاملSigns of Upper Airway Collapsibility in Snoring Sounds
We have shown that snoring fundamental frequency (F0) contours have an oscillating pattern in patients with obstructive sleep apnea (OSA) as compared to the relatively smoother pattern in simple snorers. This points to the underlying upper airway instability and collapsibility in OSA. The 2 patterns were classified by 75% accuracy.
متن کاملA model of a snorer's upper airway.
In snorers, the physiologic decrease of postural muscle tone during sleep results in increased collapsibility of the upper airway. Measurement of nasal pressure changes with prongs is increasingly used to monitor flow kinetics through a collapsing upper airway. This report presents a mathematical model to predict nasal flow profile from three critical components that control upper airway patenc...
متن کاملObesity and risk of sleep related upper airway obstruction in Caucasian children.
BACKGROUND Obesity is thought to be a significant risk factor for upper airway obstruction during sleep in children. However, the moderating influences of age and ethnicity have not been well explored and the relative contribution of obesity per se to upper airway obstruction has yet to be quantified. Given the markedly increasing prevalence of childhood obesity, an objective understanding of t...
متن کاملUpper airway collapsibility, and contractile and metabolic characteristics of musculus uvulae.
Physiologic, metabolic, and histochemical characteristics of one upper airway (UA) dilator muscle (musculus uvulae; MU) differ between sleep apnea hypopnea syndrome (SAHS) and nonapneic snorers. We hypothesized that these differences in MU characteristics could result from the cumulative effects of the diurnal and nocturnal intermittent contractions of UA muscles in order to compensate for a pe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Acta oto-laryngologica
دوره 120 8 شماره
صفحات -
تاریخ انتشار 2000